From the fifteenth-century Ponte Sisto, erected to connect Trastevere to the center of the city, you get to Piazza Farnese.
 From here you getto Via Giulia, a straight road parallel to the river. On the way are renowned palaces, (Sacchetti and Falconieri) and important churches (San Giovanni dei Fiorentini, Santa Maria of the Oration and Death). You get then to piazza di Campo de’ Fiori that, with its open market, stilI pre­serves a lively and popular atmosphere while, at night, it becomes a meeting place for renowned restaurants and nightclubs. The Palazzo della Cancelleria, which names the homonymous square, was for several centuries site of the Apostle Chancellery, the Pope’s Offices. Beyond the Corso Vittorio Emanuele, you get to Piazza Navona.  

At the center of the square is the Fountain of the Rivers that faces the church of Sant’Agnese in Agone. 

From the square you get to via del Governo Vecchio. The road was crossed by Dante during the Jubilee in 1300.The road brings to the Tiber embarkment, in the vicinity of Ponte Sant’Angelo. 

On the opposite side is Castel Sant’Angelo. In the Middle Ages, it was changed into a fortress.  By crossing via della Conciliazione you get to the Basilica of St. Peter.